There is no point in coming up with a new idea for a business, medicine or drug, service, or other company if it is not both unique and meaningful. To be unique means to be at least a little different than your competitors, for better or for worse. To be meaningful means to have a function or purpose that some identifiable subset of people will benefit from. It is easy to think of meaningful ideas that other people have already thought of, likewise, it is pretty simple to think of unique ideas, but most are wildly impractical. So the idea process happens best either by thinking of a practical idea, then expanding out to how it could become a unique idea, or to do the opposite, thinking of completely unique idea and looking for a way to make it practical. The graph below shows three points, one that is very unique and not meaningful, one that is the opposite, and one that is both. The optimal idea on this chart is fairly unique and even more meaningful, which would be the ideal combination, as the practicality and meaningfulness of an idea is obviously a bit more important than its complete uniqueness.
This is a framework I have been taught and am appreciative that I got this training. It has helped me come up with many ideas, even if I have rarely decided to take the initiative to act on them. Happy idea hunting!