The best joint supplements on the market can help ease joint pain caused by inflammatory conditions such as arthritis. However, drug store shelves are lined with products that claim to reduce painful joints but don't actually live up to these claims. How do you know which one to choose? Try sticking with the supplements that have been scientifically proven to reduce inflammation and pain in joints. In this article, we'll take a look at the best joint supplement on the market, as well as a few others that can effectively provide relief.

The Best: Glucosamine and Chondroitin

Without a doubt, the absolute best joint supplement available today is a combination of Glucosamine and Chondroitin. Of the many different brands, GNC's TriFlex Glucosamine and Chondroitin consistently receives good reviews from users. It's a high-quality supplement with very little filler and it contains MSM, an organic sulfur found in the joint cartilage and connective tissues of the joints. This means it has even more power to support joint health and reduce pain and inflammation. Let's look at the science behind this supplement.

Glucosamine, a type of amino sugar, occurs naturally in the human body and has been proven to reduce joint pain. The body's production of the substance decreases with age, which is usually when joint problems begin. The National Institutes of Health conducted a study in 2006 that found people suffering from osteoarthritis with moderate to severe knee pain experienced a significant reduction in pain after being treated with the supplement. Kevin R. Stone, Chairman of the Stone Foundation for Sports Medicine and Arthritis Research in San Francisco, observed that the supplement worked just as well as the prescription drug Celebrex, but without the unwanted side effects. Chondroitin, another naturally occurring substance found in the human body, only adds to the effectiveness of the duo. It is a component in our cartilage and prevents painful compression of the joints.

Even people who do not have arthritis and just want to prevent future joint pain or keep their joints healthy can benefit from taking Glucosamine and Chondroitin. The supplement is especially helpful for individuals over the age of 40. According to Dr. Andrew Weil, MD, individuals weighing between 120 and 200 lbs. should take 1,500 mg of glucosamine and 1,200 mg of chondroitin each day. Please note that it may take up to two months before you acheive noticeable results.

Pretty Good: Sam-E

You may have heard of this product being marketed as a general wellness aid, but it's also one of the best joint supplements available today. Sam-E is another naturally occurring molecule that provides sulfur to the body's cartilage, which in turn builds strong, healthy joints. According to a study published in the Journal of Family Practice in May 2002, Sam-E is just as effective as ibuprofen and aspirin at treating the pain caused by arthritis. Dr. Weil recommends taking 400 mg of Sam-E twice a day for two weeks, and then decreasing the dosage to 200 mg twice a day. Again, it can take several months to yield full results, so have patience. There are a few different brands available, but the one that users consistently give top scores is Doctor's Best Double Strength Sam-E.


Although these are some of the best supplements for joint pain on the market, and are generally considered safe, you should always consult your doctor before you begin taking any new dietary supplements. This is especially true if you currently take prescription medications, as side effects could occur. Also, be sure to discuss any chronic undiagnosed joint pain with your doctor, as this may an indication of arthritis or other serious medical conditions.